Watch our video about the RaniPill™ capsule.
Millions of patients with chronic conditions require biologic drugs that today can only be injected. These injections are painful and inconvenient and often affect both patient compliance and quality of life. Patient aversion to injections has promoted a significant interest in the development of solutions to enable the oral delivery of biologics, and we believe the solution is the RaniPill™ capsule. Our preclinical and clinical studies have demonstrated delivery with high bioavailability, similar to subcutaneous injections, with several molecules.Learn More
Find Out How Our Pill Works.
The RaniPill™ capsule is swallowed by the patient and makes its way past the stomach to the intestine.
Once the RaniPill™ capsule reaches the intestine, the outer shell dissolves and the balloon starts to inflate, revealing the delivery mechanism.
Pressure in the balloon pushes a microneedle into the intestinal wall. The drug is absorbed with bioavailability similar to a subcutaneous injection.
Octreotide can lower levels of excess growth hormone for the treatment of acromegaly.
TNF-alpha (TNFα) inhibitors are used to treat a range of inflammatory disorders and autoimmune conditions including psoriasis, rheumatoid arthritis, and Crohn’s disease.
Commonly used for the treatment of osteoporosis and hypoparathyroidism, PTH increases the concentration of calcium in the blood.
Human Growth Hormone (HGH) is a peptide hormone that stimulates growth, cell reproduction and regeneration.
Glucagon-like peptide-1 agonists, or GLP-1 mimetics, are a class of drugs used in the treatment of Type II diabetes by increasing insulin secretion and suppressing glucagon secretion.
Basal insulin or “background insulin” is used in diabetes management as a way to regulate glucose levels in between meals.
The RaniPill™ capsule has broad applications for the treatment of NETs and acromegaly, rheumatoid arthritis, psoriatic arthritis, growth hormone deficiency, osteoporosis, Crohn’s disease, hemophilia, diabetes, among other diseases.More details